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Sickle Cell Disease

Sickle Cell Disease
Sickle Cell Disease

In sickle cell disease, the red blood cells contain an abnormal form of hemoglobin (hemoglobin S). When red blood cells contain a large amount of hemoglobin S, they can become deformed into a sickle shape. Because the sickle cells are stiff, they have difficulty traveling through the smallest blood vessels (capillaries), blocking blood flow and reducing oxygen supply to tissues in areas where capillaries are blocked.