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antibacterial drugs with a chemical structure unrelated to other known antibiotics. It is a bactericidal drug that disrupts cell wall synthesis by inhibiting phosphoenolpyruvate synthetase and thus interferes with the production of peptidoglycan.
Pharmacokinetics
Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA)
Enterobacterales (formerly Enterobacteriaceae), including extended-spectrum beta-lactamase (ESBL)–producing and carbapenem-resistant Klebsiella pneumoniae
Escherichia coli, including fluoroquinolone-resistant E. coli
Pseudomonas aeruginosa, which has variable rates of resistance
Use During Pregnancy and Breastfeeding
Drugs Mentioned In This Article
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