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Epidemic Pleurodynia

(Bornholm Disease; Bornholm's Disease)

By Mary T. Caserta, MD, Professor of Pediatrics, Division of Infectious Diseases; Attending Physician, University of Rochester School of Medicine and Dentistry; Golisano Children’s Hospital at Strong, University of Rochester Medical Center

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Epidemic pleurodynia is a febrile disorder caused most commonly by a group B coxsackievirus. Infection causes severe pleuritic chest or abdominal pain.

Epidemic pleurodynia may occur at any age but is most common among children.


Severe, frequently intermittent, often pleuritic pain begins suddenly in the epigastrium, abdomen, or lower anterior chest, with fever and often headache, sore throat, and malaise. The involved truncal muscles may become swollen and tender. Symptoms usually subside in 2 to 4 days but may recur within a few days and persist or recur for several weeks.

Cases are infrequently complicated by aseptic meningitis, orchitis, and, less commonly, myopericarditis. After recovery, subsequent infection with another group B coxsackievirus is possible.


  • Clinical evaluation

Diagnosis may be obvious in a child who has unexplained severe pleuritic or abdominal pain during an epidemic. However, in other situations, symptoms may be hard to distinguish from those due to other conditions that cause chest or abdominal pain.

Laboratory diagnosis is not routinely necessary; it consists of detecting the virus in a throat or stool sample or, less commonly, demonstrating seroconversion.


  • Symptom relief, including NSAIDs

Treatment includes NSAIDs and other symptomatic measures.