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(Fissure in Ano; Anal Ulcer)
An anal fissure is a tear or ulcer in the lining of the anus.
Anal fissures may be caused by an injury from a hard or large bowel movement or from frequent loose bowel movements. Uncommonly, they may also be caused by penetration of the anus during anal sex. Fissures cause the anal sphincter to go into spasm, which worsens pain and prevents healing.
A stool softener or psyllium or increased dietary fiber may reduce the possibility of reinjury by hard or large bowel movements. Healing is sometimes aided by use of protective zinc oxide ointments or bland suppositories (such as glycerin) that lubricate the lower rectum and soften stool.
Applying topical anesthetics (such as benzocaine or lidocaine) to the anus or soaking in a warm sitz bath for 10 to 15 minutes after each bowel movement eases discomfort and helps increase blood flow, which promotes healing. The soaking is accomplished by squatting or sitting in a partially filled tub or using a container filled with warm water placed on the toilet bowl or commode.
Treatments to reduce sphincter spasm and promote healing of fissures include injecting the sphincter with botulinum toxin and applying nitroglycerin ointment or calcium channel blockers (such as nifedipine cream or diltiazem gel) to the area of the fissure.
If these measures do not work, surgery may be needed. Sphincter spasm can be relieved by cutting a portion of the internal sphincter (internal anal sphincterotomy). The anal canal can also be stretched (controlled anal dilation).
Generic NameSelect Brand Names
diltiazemCARDIZEM, CARTIA XT, DILACOR XR
nifedipineADALAT CC, PROCARDIA
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