Not Found
Locations

Find information on medical topics, symptoms, drugs, procedures, news and more, written in everyday language.

* This is the Consumer Version. *

Fluke Infections of the Lungs

By Richard D. Pearson, MD, University of Virginia School of Medicine

Certain species of flukes cause infections of the lungs.

  • People are infected when they swallow cysts containing fluke larvae in raw, undercooked, or pickled freshwater crabs or crayfish.

  • Infected people may have diarrhea, abdominal pain, fever, cough, itching, and later symptoms due to damage to the lungs and other organs.

  • Doctors diagnose the infection when they see eggs in a person's sputum or stool.

  • Praziquantel or another drug is given to eliminate the flukes from the body.

Lung flukes include

  • Paragonimus westermani, which causes paragonimiasis

People get lung fluke infections when they swallow cysts containing immature flukes (larvae) in raw, undercooked, or pickled freshwater crabs or crayfish. These infections occur most often in the Far East.

After the cysts are swallowed, the larvae leave the cyst, penetrate the wall of the intestine and enter the abdominal cavity. Then they pass through the diaphragm, and invade the lungs. There, they develop into adults and produce eggs. The worms may also go to the brain, liver, lymph nodes, skin, or spinal cord and develop there. However, the life cycle cannot be completed because the eggs have no way to exit the body.

From the lungs, eggs are passed in the sputum that is coughed up and spit out or swallowed and passed in stool. If the eggs enter fresh water, they hatch into larvae that are ingested by snails. Inside the snail, the larvae develop into a form (called cercariae) that can swim. Cercariae released from infected snails then infect crabs or crayfish and form cysts (called metacercariae).

Symptoms

Soon after people are infected, they may have diarrhea, abdominal pain, fever, cough, and itching. Later, the infection damages the lungs the most but may affect other organs. People slowly develop symptoms such as a chronic cough, chest pain, and difficulty breathing. They may cough up blood.

If the brain is affected, people may have seizures, difficulty using or understanding language, or problems seeing. They may be paralyzed.

Diagnosis

  • Examination of a sputum or stool sample

  • Sometimes blood tests to detect antibodies to the parasite

Doctors diagnose liver fluke infections when they see eggs in a person's sputum or stool. Sometimes a sample of fluid is removed from the lungs and checked for eggs. Blood tests to detect antibodies to the parasite may be useful. ( Antibodies are proteins produced by the immune system to help defend the body against attack, including by that by parasites.)

Other tests, such as an x-ray or computed tomography (CT) of the chest, may be done to check for damage to the lungs or other organs.

Prevention

For travelers to areas where these infections are common, prevention involves not eating raw or undercooked freshwater crabs and crayfish.

Treatment

  • A drug to eliminate the flukes from the body (an antihelminthic drug)

  • Sometimes surgery

Liver fluke infections are treated with praziquantel, a drug used to eliminate flukes from the body. Other options are triclabendazole or bithionol (but this drug has more side effects).

Sometimes surgery is needed to remove growths on the skin or rarely cysts in the brain.

Resources In This Article

Drugs Mentioned In This Article

  • Generic Name
    Select Brand Names
  • BILTRICIDE

* This is the Consumer Version. *