The blood flow to the kidneys needs to be intact for the kidneys to function properly. Any interruption of or reduction in the blood flow can cause kidney damage or dysfunction and, if long-standing, increased blood pressure. When blood flow in the arteries supplying the kidneys is completely blocked, the entire kidney or a portion of the kidney supplied by that artery dies (kidney infarction). Kidney infarction can lead to kidney failure.
Blood vessel disorders of the kidneys have a number of causes, including blockages in the renal arteries or veins, inflammation of blood vessels (vasculitis), injury to the kidneys or blood vessels, and other disorders. For example, systemic sclerosis (scleroderma) and sickle cell anemia can affect the kidneys, sometimes leading to chronic kidney failure. Systemic sclerosis that affects the kidneys can also cause malignant hypertension.
Last full review/revision December 2007 by Seyed-Ali Sadjadi, MD