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Solvent Inhalants

By Patrick G. O’Connor, MD, MPH, Professor of Medicine; Chief, Section of General Internal Medicine, Yale University School of Medicine

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Adolescents use inhalants more frequently than cocaine or LSD but less frequently than marijuana or alcohol. In the United States, about 10% of adolescents have inhaled solvents. Inhalant use is particularly a problem among children aged 12 and younger. Inhalants are found in many common household products. Thus, children and adolescents can easily obtain them.

The product may be sprayed into a plastic bag and inhaled (bagging, sniffing, or snorting), or a cloth soaked with the product may be placed next to the nose or in the mouth (huffing).


Users rapidly become intoxicated. They may become dizzy, drowsy, and confused. Speech may be slurred. They may have difficulty standing and walking, resulting in an unsteady gait. Users may also become excited—but not because the solvents are stimulants. Later, perceptions and sense of reality may be distorted, resulting in illusions, hallucinations, and delusions. Users experience a euphoric, dreamy high, culminating in a short period of sleep. They may become delirious and confused, with mood swings. Thinking and coordination may be impaired. Intoxication can last anywhere from a few minutes to more than an hour.

Death can occur suddenly, even the first time one of these products is directly inhaled, because breathing becomes very slow and shallow or because heart rhythm is disturbed (called arrhythmia).

With chronic use, people become somewhat tolerant of the solvent’s effects. People may become psychologically dependent on solvents, with a strong urge to continue using the solvents. But physical dependence does not occur. That is, stopping the drug does not cause unpleasant symptoms (withdrawal).

Chronic use or exposure to solvents (including exposure in the workplace) can severely damage the brain, heart, kidneys, liver, and lungs. In addition, bone marrow may be damaged, impairing red blood cell production and causing anemia.


Treating children and adolescents who use inhalants involves evaluating any organ damage. Education and counseling to improve mental health and social skills and to manage sociologic problems may help. Recovery rates from inhalant use are among the poorest for any mood-altering substance. However, most users stop by the end of adolescence.

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* This is the Consumer Version. *