Glanders is a contagious, short- or longterm, usually fatal disease of horses caused by the bacterium Burkholderia mallei. The disease is characterized by the development of a series of ulcerating nodules. The nodules are most commonly found in the upper respiratory tract, lungs, and skin. Humans, cats, dogs, and other species are susceptible, but infections in cats are uncommon. Infections in humans are often fatal.
There is no vaccine for glanders. Prevention and control depend on early detection and elimination of affected animals. Complete quarantine and rigorous disinfection is required for all housing and objects that have been in contact with the infected animal. Euthanasia is usually recommended for infected animals (see Disorders Affecting Multiple Body Systems of Horses: Glanders (Farcy) in Horses).
Last full review/revision July 2011 by Otto M. Radostits, CM, DVM, MSc, DACVIM (Deceased); Eugene D. Janzen, DVM, MVS; Jodie Low Choy, BVMS; Dennis W. Macy, MS, DACVIM; Dudley L. McCaw, DVM, DACVIM (Small Animal, Oncology); Barton W. Rohrbach, VMD, MPH, DACVPM; J. Glenn Songer, PhD; Richard A. Squires, BVSc (Hons), PhD, DVR, DACVIM, DECVIM-CA, MRCVS; Bert E. Stromberg, PhD; Joseph Taboada, DVM, DACVIM; Charles O. Thoen, DVM, PhD; John F. Timoney, MVB, PhD, Dsc, MRCVS; Ian Tizard, BVMS, PhD, DACVM; Max J. Appel, DMV, PhD; David A. Ashford, DVM, MPH, DS; Stephen C. Barr, BVSc, MVS, PhD, DACVIM; J. P. Dubey, MVSc, PhD; Paul Ettestad, DVM, MS; Craig E. Greene, DVM, MS; Delores E. Hill, PhD; Johnny D. Hoskins, DVM, PhD