Glanders is a contagious, short or longterm, usually fatal disease of horses caused by the bacterium Burkholderia mallei. The disease is characterized by the development of a series of ulcerating nodules. The nodules are most commonly found in the upper respiratory tract, lungs, and skin. Humans, dogs, cats, and other species are susceptible, but infections in dogs are uncommon. Infections in humans are often fatal.
Prevention and control depend on early detection and elimination of affected animals. Complete quarantine and rigorous disinfection is required for all housing and objects that have been in contact with the infected animal. Euthanasia is usually recommended for infected animals. (For a more detailed discussion of Glanders, see Disorders Affecting Multiple Body Systems of Horses: Glanders (Farcy) in Horses.)
Last full review/revision July 2011 by Otto M. Radostits, CM, DVM, MSc, DACVIM (Deceased); David A. Ashford, DVM, MPH, DS; Craig E. Greene, DVM, MS; Eugene D. Janzen, DVM, MVS; Bert E. Stromberg, PhD; Max J. Appel, DMV, PhD; Stephen C. Barr, BVSc, MVS, PhD, DACVIM; J. P. Dubey, MVSc, PhD; Paul Ettestad, DVM, MS; Kenneth R. Harkin, DVM, DACVIM; Delores E. Hill, PhD; Johnny D. Hoskins, DVM, PhD; Jodie Low Choy, BVMS; Barton W. Rohrbach, VMD, MPH, DACVPM; J. Glenn Songer, PhD; Joseph Taboada, DVM, DACVIM; Charles O. Thoen, DVM, PhD; John F. Timoney, MVB, PhD, Dsc, MRCVS; Ian Tizard, BVMS, PhD, DACVM