Eosinophilic granuloma complex is rare in dogs. It is recognized more commonly in cats and horses. When seen in the dog, this disorder is associated with unusual reactions to insect bites or other hypersensitivity reactions. They will often appear as bumps or nodules anywhere on the body. Over time, these may become ulcerated or crusted. There is also a condition of unknown cause that most commonly is seen in the oral cavity of Siberian Huskies, where single or multiple nodules can appear on the tongue or in the mouth.

Some cases can be treated with antibiotics initially, although many dogs require corticosteroids. Insect control may be of some value. If the disorder returns, low-dose, corticosteroid treatment may be prescribed.

Last full review/revision July 2011 by Karen A. Moriello, DVM, DACVD; Patricia D. White, DVM, MS, DACVD; Michael W. Dryden, DVM, PhD; Carol S. Foil, DVM, MS, DACVD; William W. Hawkins, BS, DVM; Thomas R. Klei, PhD; John E. Lloyd, BS, PhD; Bernard Mignon, DVM, PhD, DEVPC; Wayne Rosenkrantz, DVM, DACVD; David Stiller, MS, PhD; Patricia A. Talcott, MS, DVM, PhD, DABVT; Alice Villalobos, DVM, DPNAP; Stephen D. White, DVM, DACVD