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Andexanet as an Antidote for Oral Anti-Factor Xa Anticoagulants—Commentary

The control of serious bleeding episodes in patients who are chronically anticoagulated with oral warfarin can be controlled/reversed by the administration of vitamin K and fresh-frozen plasma. In contrast, a limitation of the newer oral anticoagulants has been the absence of any agent that can... Continue

By Joel L. Moake, MD, Senior Research Scientist, Rice University; Professor of Medicine (Emeritus), Baylor College of Medicine

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