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Other Gingival Disorders

by James T. Ubertalli, DMD

Hyperplasia of gingival tissues may occur without inflammation in response to various drugs, particularly the following:

  • Phenytoin

  • Cyclosporine

  • Nifedipine and other Ca channel blockers

Hyperplasia is characterized by diffuse, relatively avascular smooth or nodular enlargement of the gingiva, which may almost cover some teeth. The hypertrophied tissue is often excised. If possible, substitutions are made for the offending drugs. Scrupulous oral hygiene may minimize recurrence.

Carcinoma can also originate in the gingiva and spread to regional lymph nodes.

Drugs Mentioned In This Article

  • Drug Name
    Select Trade
  • NEORAL, SANDIMMUNE
  • ADALAT CC, PROCARDIA
  • DILANTIN

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