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Atypical fibroxanthoma is a low-grade sarcoma of the skin.
Atypical fibroxanthomas most commonly occur on the head and neck of elderly patients. They appear similar to other nonmelanoma skin cancers, as nonhealing or tender pink-red skin papules or nodules. They are diagnosed with biopsy. Tumors are excised or Mohs micrographic surgery is done if clinically appropriate. Metastasis is unusual.
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