* This is the Professional Version. *
Herpes Zoster Oticus
(Geniculate Herpes; Ramsay Hunt Syndrome; Viral Neuronitis)
Patient Education
- Inner Ear Disorders
- Introduction to Inner Ear Disorders
- Acoustic Neuroma
- Benign Paroxysmal Positional Vertigo
- Drug-Induced Ototoxicity
- Herpes Zoster Oticus
- Meniere Disease
- Purulent Labyrinthitis
- Vestibular Neuronitis
Herpes zoster oticus is an uncommon manifestation of herpes zoster that affects the 8th cranial nerve ganglia and the geniculate ganglion of the 7th (facial) cranial nerve.
Herpes zoster (shingles) is reactivation of varicella-zoster virus infection. Risk factors for reactivation include immunodeficiency secondary to cancer, chemotherapy, radiation therapy, and HIV infection. Typically, the virus remains latent in a dorsal root ganglion, and reactivation manifests as painful skin lesions following a dermatomal distribution. However, rarely the virus remains latent in the geniculate ganglion and upon reactivation causes symptoms involving the 7th and 8th cranial nerves.
Symptoms and Signs
Diagnosis
Treatment
Although there is no reliable evidence that corticosteroids, antiviral drugs, or surgical decompression makes a difference, they are the only possibly useful treatments. When used, corticosteroids are started with prednisone 60 mg po once/day for 4 days, followed by gradual tapering of the dose over the next 2 wk. Either acyclovir 800 mg po 5 times/day or valacyclovir 1 g po bid for 10 days may shorten the clinical course and is routinely prescribed for immunocompromised patients.
Vertigo is effectively suppressed with diazepam 2 to 5 mg po q 4 to 6 h. Pain may require oral opioids. Postherpetic neuralgia may be treated with amitriptyline.
Surgical decompression of the fallopian canal may be indicated if the facial palsy is complete (no visible facial movement), but must be performed within 2 wk of onset of the facial paralysis to be effective. Before surgery, however, electroneurography is done and should show a >90% decrement.
Drugs Mentioned In This Article
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Drug NameSelect Trade
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amitriptylineNo US brand name
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valacyclovirVALTREX
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diazepamVALIUM
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prednisoneRAYOS
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acyclovirZOVIRAX
- Inner Ear Disorders
- Introduction to Inner Ear Disorders
- Acoustic Neuroma
- Benign Paroxysmal Positional Vertigo
- Drug-Induced Ototoxicity
- Herpes Zoster Oticus
- Meniere Disease
- Purulent Labyrinthitis
- Vestibular Neuronitis
* This is the Professional Version. *





Kimia
Meghan