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Vestibular Neuronitis

Vestibular neuronitis causes a self-limited episode of vertigo, presumably due to inflammation of the vestibular division of the 8th cranial nerve; some vestibular dysfunction may persist.

Although etiology is unclear, a viral cause is suspected.

Symptoms and Signs

Symptoms include a single attack of severe vertigo, with nausea and vomiting and persistent nystagmus toward the affected side, which lasts 7 to 10 days. The nystagmus is unidirectional, horizontal, and spontaneous, with fast-beat oscillations in the direction of the unaffected ear. The absence of concomitant tinnitus or hearing loss is a hallmark of vestibular neuronitis. The condition slowly subsides after this initial episode. Some patients have residual dysequilibrium, especially with rapid head movements, probably due to permanent vestibular injury.

Diagnosis

  • Audiology, electronystagmography, and MRI

Patients undergo an audiologic assessment, electronystagmography with caloric testing, and gadolinium-enhanced MRI of the head, with attention to the internal auditory canals to exclude other diagnoses, such as cerebellopontine angle tumor, brain stem hemorrhage, or infarction. MRI may show enhancement of the vestibular nerves, consistent with inflammatory neuritis.

Treatment

  • Symptom relief with antiemetics, antihistamines, or benzodiazepines

Symptoms are addressed as in Meniere's disease (see Inner Ear Disorders: Treatment), ie, with anticholinergics, antiemetics (eg, prochlorperazineSome Trade Names
COMPAZINE
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or promethazineSome Trade Names
PHENERGAN
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25 mg rectally or 10 mg po q 6 to 8 h), antihistamines or benzodiazepines, and a corticosteroid burst with rapid taper. If vomiting is prolonged, IV fluids and electrolytes may be required. Vestibular rehabilitation (usually given by a physical therapist) helps compensate for any residual vestibular deficit.

Last full review/revision July 2007 by John S. Oghalai, MD

Content last modified July 2007

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