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Introduction to Renal Transport Abnormalities

by James I. McMillan, MD

Many substances are secreted or reabsorbed in the renal tubule system, including electrolytes, protons, HCO 3 molecules, and free water. Dysfunction of these processes can result in clinical syndromes. Syndromes are inherited, acquired, or both. Syndromes that almost always manifest in childhood (eg, Bartter syndrome, Gitelman syndrome, cystinuria, Hartnup disease, and hypophosphatemic rickets) are discussed in Congenital Renal Transport Abnormalities.

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