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Phyllodes Tumor

(Cystosarcoma Phyllodes)

By Mary Ann Kosir, MD, Wayne State University School of Medicine; Walt Breast Center, Karmanos Cancer Institute

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Phyllodes tumor is a nonepithelial breast tumor that may be benign or malignant.

Tumors are frequently large (4 to 5 cm) at diagnosis. About half are malignant, accounting for < 1% of breast cancers. Between 20% and 35% of these tumors recur locally, and distant metastases occur in 10 to 20% of patients.

Usual treatment is wide excision, but a mastectomy may be more appropriate if the mass is large or histology suggests cancer. Radiation therapy may be recommended in some cases.

Prognosis is good unless metastases (usually pulmonary) are present.

* This is the Professional Version. *