Sections
Index
Symptoms
Cardiovascular Disorders
Clinical Pharmacology
Critical Care Medicine
Dental Disorders
Dermatologic Disorders
Ear, Nose, and Throat Disorders
Endocrine and Metabolic Disorders
Eye Disorders
Gastrointestinal Disorders
Genitourinary Disorders
Geriatrics
Gynecology and Obstetrics
Hematology and Oncology
Hepatic and Biliary Disorders
Immunology; Allergic Disorders
Infectious Diseases
Injuries; Poisoning
Musculoskeletal and Connective Tissue Disorders
Neurologic Disorders
Nutritional Disorders
Pediatrics
Psychiatric Disorders
Pulmonary Disorders
Special Subjects
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Abdominal Pain, Acute
Abdominal pain, Chronic
Alopecia
Amenorrhea
Amnesia
Anosmia
Bleeding, Excessive
Breast Lumps
Chest Pain
Constipation in Adults
Constipation in Children
Cough in Adults
Cough in Children
Crying
Diarrhea in Adults
Diarrhea in Children
Diplopia
Dizziness
Dry Mouth
Dysmenorrhea
Dyspepsia
Dysphagia
Dyspnea
Dysuria
Earache
Ear Discharge
Edema
Edema During Late Pregnancy
Epistaxis
Erectile dysfunction
Eyelid Swelling
Eye Pain
Fever
Fever, Acute, in Adults
Fever, Chronic (FUO)
Fever in Infants and Children
Floaters
Gas
Gastrointestinal Bleeding
Halitosis
Headache
Hearing Loss
Hearing Loss: Sudden Deafness
Hematospermia
Hematuria
Hemoptysis
Hiccups
Hirsutism
Insomnia and Excessive Daytime Sleepiness
Itching
Itching, Anal
Jaundice in Adults
Jaundice in Neonates
Joint Pain, Monarticular
Joint Pain, Polyarticular
Knee pain
Lump in Throat
Nasal Congestion and Rhinorrhea
Nausea and Vomiting During Early pPregnancy
Nausea and Vomiting in Adults
Nausea and Vomiting in Infants and Children
Neck and Back Pain
Neck Mass
Nipple Discharge
Orthostatis Hypotension
Pain
Pain, Chronic
Palpitations
Pelvic Pain
Pelvic Pain During Early Pregnancy
Polyuria
Priapism
Red Eye
Scrotal Pain
Sore Throat
Stomatitis
Stridor
Syncope
Tearing
Tinnitus
Toothache
Tremor
Urinary Frequency
Urinary Incontinence in Adults
Urinary Incontinence in Children
Urinary Retention
Urticaria
Vaginal Bleeding
Vaginal Bleeding During Early Pregnancy
Vaginal Bleeding During Late Pregnancy
Vaginal Itching and Discharge
Vision, Blurred
Vision Loss, Acute
Weakness, Generalized
Wheezing
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Sections
in
Health Care Professionals
Cardiovascular Disorders
Clinical Pharmacology
Critical Care Medicine
Dental Disorders
Dermatologic Disorders
Ear, Nose, and Throat Disorders
Endocrine and Metabolic Disorders
Eye Disorders
Gastrointestinal Disorders
Genitourinary Disorders
Geriatrics
Gynecology and Obstetrics
Hematology and Oncology
Hepatic and Biliary Disorders
Immunology; Allergic Disorders
Infectious Diseases
Injuries; Poisoning
Musculoskeletal and Connective Tissue Disorders
Neurologic Disorders
Nutritional Disorders
Pediatrics
Psychiatric Disorders
Pulmonary Disorders
Special Subjects
Merck Manual
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Health Care Professionals
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Immunology; Allergic Disorders
Immunology; Allergic Disorders
Biology of the Immune System
Overview of the Immune System
Innate immunity
Acquired immunity
Immune Response
Activation
Regulation
Resolution
Geriatrics Essentials
Components of the Immune System
Antigen-Presenting Cells
Polymorphonuclear Leukocytes
Cytotoxic Leukocytes
Natural killer (NK) cells
Lymphokine-activated killers (LAK)
Lymphocytes
B cells
T cells
Antibodies
Structure
Antibody classes
Acute Phase Reactants
Cytokines
Human Leukocyte Antigen (HLA) System
Complement System
Biologic activities
Immunotherapeutics
Monoclonal antibodies
Fusion proteins
Soluble cytokine receptors
Recombinant cytokines
Small-molecule mimetics
Cellular therapies
Immunodeficiency Disorders
Overview of Immunodeficiency Disorders
Secondary immunodeficiencies
Primary immunodeficiencies
Geriatrics Essentials
Approach to the Patient With Suspected Immunodeficiency
Evaluation
History
Physical examination
Initial testing
Additional testing
Prenatal diagnosis
Prognosis
Treatment
Infection prevention
Management of acute infection
Replacement of missing immune components
Ataxia-Telangiectasia
Diagnosis
Treatment
Chédiak-Higashi Syndrome
Chronic Granulomatous Disease
Symptoms and Signs
Diagnosis
Treatment
Chronic Mucocutaneous Candidiasis
Diagnosis
Treatment
Common Variable Immunodeficiency
Diagnosis
Treatment
DiGeorge Syndrome
Diagnosis
Treatment
Hyper-IgE Syndrome
Hyper-IgM Syndrome
Diagnosis
Treatment
IgA Deficiency
Symptoms and Signs
Diagnosis
Prognosis
Treatment
Leukocyte Adhesion Deficiency
Diagnosis
Treatment
Severe Combined Immunodeficiency (SCID)
Symptoms and Signs
Diagnosis
Treatment
Transient Hypogammaglobulinemia of Infancy
Wiskott-Aldrich Syndrome
Diagnosis
Treatment
X-linked Agammaglobulinemia
Diagnosis
Treatment
X-linked Lymphoproliferative Syndrome
Diagnosis
Treatment
ZAP-70 Deficiency
Allergic, Autoimmune, and Other Hypersensitivity Disorders
Overview of Allergy and Atopy
Classification of Hypersensitivity Reactions
Type I
Type II
Type III
Type IV
Atopic and Allergic Disorders
Etiology
Allergens
Pathophysiology
Symptoms and Signs
Diagnosis
Nonspecific tests
Specific tests
Treatment
Environmental control
H
1
blockers
Mast cell stabilizers
Anti-inflammatory drugs
Immunotherapy
Prevention
Key Points
Allergic Rhinitis
Symptoms and Signs
Diagnosis
Treatment
Key Points
Food Allergy
Etiology
Eosinophilic gastroenteropathy
Symptoms and Signs
Diagnosis
Treatment
Key Points
Anaphylaxis
Etiology
Pathophysiology
Anaphylactoid reactions
Symptoms and Signs
Diagnosis
Treatment
Prevention
Key Points
Angioedema
Acute angioedema
Chronic angioedema
Hereditary and acquired angioedema
Symptoms and Signs
Diagnosis
Treatment
Key Points
Hereditary and Acquired Angioedema
Hereditary angioedema
Acquired C1 inhibitor deficiency
Triggers
Symptoms and Signs
Diagnosis
Treatment
Key Points
Autoimmune Disorders
Etiology
Mechanisms
Genetic factors
Defense mechanisms
Drug Hypersensitivity
Pathophysiology
Symptoms and Signs
Diagnosis
Skin testing
Other testing
Prognosis
Treatment
Desensitization
Key Points
Mastocytosis
Classification
Cutaneous mastocytosis
Systemic mastocytosis
Symptoms and Signs
Diagnosis
Treatment
Cutaneous mastocytosis
Systemic mastocytosis
Key Points
Transplantation
Overview of Transplantation
Organ distribution
Pretransplantation Screening
Tissue compatibility
Infection
Contraindications to transplantation
Immunosuppression
Corticosteroids
Calcineurin inhibitors (CNIs)
Purine metabolism inhibitors
Rapamycins
Immunosuppressive Igs
Monoclonal antibodies (mAbs)
Irradiation
Future therapies
Posttransplantation Complications
Rejection
Infection
Renal disorders
Cancer
Other complications
Heart Transplantation
Procedure
Complications
Prognosis
Hematopoietic Stem Cell Transplantation
Procedure
Complications
Early complications
Later complications
Prognosis
Kidney Transplantation
Procedure
Complications
Prognosis
Liver Transplantation
Procedure
Complications
Prognosis
Lung Transplantation
Procedure
Complications
Prognosis
Pancreas Transplantation
Procedure
Complications
Prognosis
Pancreatic Islet Cell Transplantation
Procedure
Small-Bowel Transplantation
Procedure
Complications
Prognosis
Tissue Transplantation
Composite transplantation (hand, extremity, face)
Skin allografts
Cartilage transplantation
Bone transplantation
Corneal transplantation
Adrenal autografting
Fetal thymus implants
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