Not Found

Find information on medical topics, symptoms, drugs, procedures, news and more, written for the health care professional.


By Hans P. Schlecht, MD, MSc, Assistant Professor of Medicine, Department of Medicine, Division of Infectious Diseases & HIV Medicine, Drexel University College of Medicine
Christopher Bruno, MD, Assistant Professor of Medicine, Division of infectious Diseases & HIV Medicine, Drexel University College of Medicine

Click here for
Patient Education

Spectinomycin is a bacteriostatic antibiotic chemically related to the aminoglycosides (see Aminoglycosides). Spectinomycin binds to the 30S subunit of the ribosome, thus inhibiting bacterial protein synthesis. Its activity is restricted to gonococci. Spectinomycin is excreted by glomerular filtration.

Indications include

  • Gonococcal urethritis

  • Cervicitis

  • Proctitis

Spectinomycin is not effective for gonococcal pharyngitis. It is not available in the US, and where available, it is reserved for patients who cannot be treated with ceftriaxone or cefixime plus azithromycin or doxycycline.

Adverse effects, including hypersensitivity reactions and fever, are rare.

Drugs Mentioned In This Article

  • Drug Name
    Select Trade