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Mupirocin

MupirocinSome Trade Names
BACTROBAN
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inhibits bacterial RNA and protein synthesis. It is available only as a 2% topical preparation, which is bactericidal against staphylococci and β-hemolytic streptococci. Systemic absorption of topical mupirocinSome Trade Names
BACTROBAN
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is negligible.

MupirocinSome Trade Names
BACTROBAN
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is used for impetigo and for minor superficial secondarily infected skin lesions. MupirocinSome Trade Names
BACTROBAN
Click for Drug Monograph
can also eradicate Staphylococcus aureus nasal carriage, although relapse rates may be high. Chronic therapy leads to mupirocinSome Trade Names
BACTROBAN
Click for Drug Monograph
-resistant staphylococci.

MupirocinSome Trade Names
BACTROBAN
Click for Drug Monograph
is nontoxic but, when applied to denuded skin or mucous membranes, may cause itching and burning.

Last full review/revision July 2009 by Matthew E. Levison, MD

Content last modified July 2009

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