Not Found

Find information on medical topics, symptoms, drugs, procedures, news and more, written for the health care professional.

Fracture-Dislocation of the Midfoot (Lisfranc Injury)

By Danielle Campagne, MD, Assistant Clinical Professor, Department of Emergency Medicine, University of San Francisco - Fresno

Click here for
Patient Education

A Lisfranc injury is a fracture and/or dislocation of the midfoot that disrupts one or more tarsometatarsal joints. Diagnosis is by x-rays and often CT. Treatment requires referral to an orthopedic surgeon and usually open reduction and internal fixation or sometimes fusion of the midfoot.

Lisfranc injuries are common. The usual mechanism is a direct blow or an indirect twisting force applied to a foot in plantar flexion (eg, fall on a foot in plantar flexion), as may occur in football players, motorcyclists, and horseback riders.

The Lisfranc joint complex consists of the 5 tarsometatarsal joints that connect the forefoot and midfoot. There are multiple ligaments in this complex. The Lisfranc ligament itself is the ligament that attaches the base of the 2nd metatarsal to the 1st cuneiform. Lisfranc complex injuries vary widely in severity from strains to dislocation of one or more tarsometatarsal joints with or without fracture. When fracture occurs, it often involves the 2nd metatarsal. Lisfranc injuries often cause instability of the midfoot.

Fracture of the 2nd metatarsal base with tarsometatarsal joint dislocation.

Fracture of the 2nd metatarsal base may disrupt one or more of the tarsometatarsal joints. In this figure, the 2nd metatarsal fracture displaces the 3rd through 5th metatarsals laterally.

Severity of Lisfranc injury varies widely. Some injuries cause only mild swelling and pain in the midfoot; others cause severe soft-tissue pain and swelling, deformity, a hematoma on the sole of the midfoot, and sometimes paresthesias. The foot may appear shortened.

Complications (eg, osteoarthritis, compartment syndrome) can be serious and chronic disability is common.


  • X-rays

  • Sometimes CT

Anteroposterior, lateral, and oblique x-rays of the foot are taken, but findings may be subtle, leading to misdiagnosis. Up to 20% of these fractures are missed at the initial presentation.

X-rays can show a fracture at the base of the 2nd metatarsal or chip fractures of the cuneiform but may not show disruption of the tarsometatarsal joint, which should be suspected even if it is not visible on plain x-rays. Normally in this joint, the medial aspect of the 2nd cuneiform aligns directly with the medial aspect of the 2nd metatarsal. Comparison views or CT may be necessary to identify disruption of the joint.

Pearls & Pitfalls

  • If the midfoot is extremely swollen and tender, closely examine the x-ray to determine whether the medial aspect of the 2nd cuneiform directly aligns with the medial aspect of the 2nd metatarsal.

If CT is not readily available, stress x-rays can be used. X-rays are taken while the foot is under stress (eg, the patient is standing on the foot). The patient's body weight can cause the space between the 1st and 2nd metatarsals to widen, making the diagnosis much easier. However, CT is more sensitive than stress x-rays and so is preferred in equivocal cases.


  • Orthopedic consultation

  • Usually, open reduction and internal fixation (ORIF) or sometimes fusion of the midfoot

Dislocations often spontaneously reduce. Nonetheless, because these injuries usually compromise foot function and cause residual pain and arthritis, patients should be immediately referred to an orthopedic specialist, usually for surgery. Typically, definitive treatment is ORIF or fusion of the midfoot.

After ORIF, CT is usually done to confirm correct alignment.

If surgery is not considered necessary, patients are immobilized, with no weight-bearing for ≥ 6 wk.

Key Points

  • Lisfranc injuries (fracture-dislocation) involve disruption of ≥ 1 ligaments that stabilize the midfoot, sometimes disrupting ≥ 1 tarsometatarsal joints.

  • Complications (eg, compartment syndrome, chronic pain, disability) may be serious.

  • Because x-ray findings may be subtle, stress x-rays or CT may be needed.

  • Refer patients to an orthopedic surgeon; usually, ORIF or fusion of the midfoot is required.

Resources In This Article