*PPV: Initiate resuscitation with room air. If SpO 2 targets are not achieved, titrate inhaled oxygen concentration upward. If HR is † For SpO 2 monitoring targets. ‡ 3:1 compression:ventilation ratio with a total of 90 compressions and 30 breaths/min. Compressions and ventilations are delivered sequentially, not simultaneously. Thus, give 3 compressions at a rate of 120/min, followed by 1 ventilation over 1/2 sec. HR = heart rate; PPV = positive pressure ventilation; SpO 2 = oxygen saturation. Adapted from the American Heart Association. Web-based Integrated Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care– Part 13: Neonatal Resuscitation . ECCguidelines.heart.org . © Copyright 2015 American Heart Association, Inc.