THE MERCK MANUAL: The Merck Manual of Diagnosis and Therapymultimedia

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Infectious Diseases

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Rubeola (Koplik's Spots)

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Rubeola (Koplik's Spots)

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  • Measles
  • Koplik's spots are classically described as being bright red spots with white or bluish-white centers that may resemble grains of sand. They may occur anywhere in the mouth, often precede the generalized exanthem, and are pathognomonic for rubeola (measles).

    Images courtesy of the Public Health Image Library of the Centers for Disease Control and Prevention.

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