THE MERCK MANUAL: The Merck Manual of Diagnosis and Therapymultimedia

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  • Smallpox
  • Vaccinia—Generalized

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    Generalized vaccinia is diffusely distributed vaccinial lesions caused by hematogenous spread of the vaccinia virus after vaccination. Despite a possibly severe appearance, generalized vaccinia is usually benign.

    Image courtesy of Dr. Allen W. Mathies of the Immunization Branch of the California Emergency Preparedness Office (Calif/EPO) via the Public Health Image Library of the Centers for Disease Control and Prevention.