THE MERCK MANUAL: The Merck Manual of Diagnosis and Therapymultimedia


  • Skin Manifestations of Internal Disease
  • Erythema Nodosum

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    Erythema Nodosum

    Erythema nodosum is a form of panniculitis characterized by palpable, tender, and red or violet subcutaneous nodules most typically appearing on the shins. It most often accompanies systemic diseases (eg, streptococcal infection, sarcoidosis, TB, inflammatory bowel disease, disseminated fungal infection) or ingestion of drugs (particularly oral contraceptives) but is often idiopathic.

    Image provided by Thomas Habif, MD.