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Many craniofacial and musculoskeletal abnormalities occur only at a single, specific site. They may be a deformity (alteration in shape due to unusual pressure and malpositioning [eg, clubfoot]) or a malformation (an error in normal organ or tissue development [eg, anencephaly]). Both deformities and malformations affect function. Some abnormalities (eg, arthrogryposis multiplex congenita) affect multiple sites.
Last full review/revision January 2010 by Gregory S. Liptak, MD, MPH
Content last modified January 2010
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