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Introduction to Connective Tissue Disorders in Children

By David D. Sherry, MD, University of Pennsylvania;The Children's Hospital of Philadelphia ; Frank Pessler, MD, PhD, Technische Universität Dresden, Germany

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There are over 200 disorders that involve connective tissue. Certain disorders are characterized by overactivity of the immune system with resulting inflammation and systemic damage to the tissues (eg, SLE [see Systemic Lupus Erythematosus (SLE)] and juvenile idiopathic arthritis [formerly known as juvenile rheumatoid arthritis—see Juvenile Idiopathic Arthritis (JIA)]). Other disorders involve biochemical abnormalities or structural defects of the connective tissue. Some of these disorders are inherited, and some are of unknown etiology.

* This is the Professional Version. *