Tumor recognition is a complex, challenging problem for the immune system, which must distinguish proper cellular growth and organization from neoplastic transformation. This process involves recognition of tumor antigens by effector cells and induction of immunity. The development of tumors despite the presence of antigens, the significance of immune recognition in the pathogenesis of tumors, and the potential for therapeutic augmentation of immune responses remain the subject of intense investigation.

Last full review/revision March 2013 by Dmitry Gabrilovich, MD, PhD