THE MERCK MANUAL: The Merck Manual of Diagnosis and Therapy
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Introduction

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Interaction between drugs and the liver can be categorized as follows:

  • Effects of liver disease on drug metabolism
  • Liver injury caused by drugs
  • Effects of hepatic drug metabolism (eg, induction of hepatic enzymes, see Pharmacokinetics: Drug Metabolism)

The number of possible interactions is vast.

Last full review/revision January 2013 by Steven K. Herrine, MD

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