Search
SectionsIndexSymptoms
  • Cardiovascular Disorders
  • Clinical Pharmacology
  • Critical Care Medicine
  • Dental Disorders
  • Dermatologic Disorders
  • Ear, Nose, and Throat Disorders
  • Endocrine and Metabolic Disorders
  • Eye Disorders
  • Gastrointestinal Disorders
  • Genitourinary Disorders
  • Geriatrics
  • Gynecology and Obstetrics
  • Hematology and Oncology
  • Hepatic and Biliary Disorders
  • Immunology; Allergic Disorders
  • Infectious Diseases
  • Injuries; Poisoning
  • Musculoskeletal and Connective Tissue Disorders
  • Neurologic Disorders
  • Nutritional Disorders
  • Pediatrics
  • Psychiatric Disorders
  • Pulmonary Disorders
  • Special Subjects
ABCDEFGHI
JKLMNOPQR
STUVWXYZ
  • Abdominal Pain, Acute
  • Abdominal pain, Chronic
  • Alopecia
  • Amenorrhea
  • Amnesia
  • Anosmia
  • Bleeding, Excessive
  • Breast Lumps
  • Chest Pain
  • Constipation in Adults
  • Constipation in Children
  • Cough in Adults
  • Cough in Children
  • Crying
  • Diarrhea in Adults
  • Diarrhea in Children
  • Diplopia
  • Dizziness
  • Dry Mouth
  • Dysmenorrhea
  • Dyspepsia
  • Dysphagia
  • Dyspnea
  • Dysuria
  • Earache
  • Ear Discharge
  • Edema
  • Edema During Late Pregnancy
  • Epistaxis
  • Erectile dysfunction
  • Eyelid Swelling
  • Eye Pain
  • Fever
  • Fever, Acute, in Adults
  • Fever, Chronic (FUO)
  • Fever in Infants and Children
  • Floaters
  • Gas
  • Gastrointestinal Bleeding
  • Halitosis
  • Headache
  • Hearing Loss
  • Hearing Loss: Sudden Deafness
  • Hematospermia
  • Hematuria
  • Hemoptysis
  • Hiccups
  • Hirsutism
  • Insomnia and Excessive Daytime Sleepiness
  • Itching
  • Itching, Anal
  • Jaundice in Adults
  • Jaundice in Neonates
  • Joint Pain, Monarticular
  • Joint Pain, Polyarticular
  • Knee pain
  • Lump in Throat
  • Nasal Congestion and Rhinorrhea
  • Nausea and Vomiting During Early pPregnancy
  • Nausea and Vomiting in Adults
  • Nausea and Vomiting in Infants and Children
  • Neck and Back Pain
  • Neck Mass
  • Nipple Discharge
  • Orthostatis Hypotension
  • Pain
  • Pain, Chronic
  • Palpitations
  • Pelvic Pain
  • Pelvic Pain During Early Pregnancy
  • Polyuria
  • Priapism
  • Red Eye
  • Scrotal Pain
  • Sore Throat
  • Stomatitis
  • Stridor
  • Syncope
  • Tearing
  • Tinnitus
  • Toothache
  • Tremor
  • Urinary Frequency
  • Urinary Incontinence in Adults
  • Urinary Incontinence in Children
  • Urinary Retention
  • Urticaria
  • Vaginal Bleeding
  • Vaginal Bleeding During Early Pregnancy
  • Vaginal Bleeding During Late Pregnancy
  • Vaginal Itching and Discharge
  • Vision, Blurred
  • Vision Loss, Acute
  • Weakness, Generalized
  • Wheezing
In This Topic
Special Subjects
Dietary Supplements
Black Cohosh
Claims
Adverse effects
Back to Top
Resources
  • About The Merck Manual
  • Ready Reference Guides
  • Trade Names of Some Commonly Used Drugs
  • Normal Laboratory Values
  • Clinical Calculators
  • Multimedia
  • Selected Links
Manuals available online
'/home/index.html' + bookPageLink
 
'/professional/index.html'
These and other Manuals available
in print, online, and as mobile applications.

See more at MerckManuals.com
Sections in Health Care Professionals
  • Cardiovascular Disorders
  • Clinical Pharmacology
  • Critical Care Medicine
  • Dental Disorders
  • Dermatologic Disorders
  • Ear, Nose, and Throat Disorders
  • Endocrine and Metabolic Disorders
  • Eye Disorders
  • Gastrointestinal Disorders
  • Genitourinary Disorders
  • Geriatrics
  • Gynecology and Obstetrics
  • Hematology and Oncology
  • Hepatic and Biliary Disorders
  • Immunology; Allergic Disorders
  • Infectious Diseases
  • Injuries; Poisoning
  • Musculoskeletal and Connective Tissue Disorders
  • Neurologic Disorders
  • Nutritional Disorders
  • Pediatrics
  • Psychiatric Disorders
  • Pulmonary Disorders
  • Special Subjects
Chapters in Special Subjects
  • General Principles of Medical Genetics
  • Clinical Decision Making
  • Principles of Radiologic Imaging
  • Complementary and Alternative Medicine
  • Dietary Supplements
  • Drug Use and Dependence
  • Tobacco Use
  • Medical Aspects of Travel
  • Syndromes of Uncertain Origin
  • Care of the Surgical Patient
  • Rehabilitation
  • Exercise
  • The Dying Patient
  • Medicolegal Issues
  • Financial Issues in Health Care
  • Limb Prosthetics
Topics in Dietary Supplements
  • Overview of Dietary Supplements
  • Black Cohosh
  • Chamomile
  • Chondroitin Sulfate
  • Chromium
  • Coenzyme Q10
  • Cranberry
  • Creatine
  • Dehydroepiandrosterone (DHEA)
  • Echinacea
  • Feverfew
  • Fish Oil
  • Garlic
  • Ginger
  • Ginkgo
  • Ginseng
  • Glucosamine
  • Goldenseal
  • Green Tea
  • Kava
  • Licorice
  • Melatonin
  • Milk Thistle
  • S-Adenosyl-l-Methionine
  • Saw Palmetto
  • St. John's Wort
  • Valerian
  • Zinc
 
  • Merck Manual
  • >
  • Health Care Professionals
  • >
  • Special Subjects
  • >
  • Dietary Supplements
  • 4
 
Black Cohosh

Share This

Black cohosh is the underground stem of a plant that can be ingested directly in powdered form or extracted into tablet or liquid form. It should be standardized to contain certain triterpenes. Black cohosh contains no phytoestrogens that can account for its purported estrogen-like effects, but it contains small amounts of anti-inflammatory compounds, including salicylic acidSome Trade Names
MEDIPLAST
PROPA PH
STRI-DEX
Click for Drug Monograph
.

Claims: Black cohosh is said to be useful for menopausal symptoms (eg, hot flushes, mood lability, tachycardia, vaginal dryness), for menstrual symptoms, and for arthralgias in RA or osteoarthritis.

Scientific evidence regarding benefit in relieving menstrual symptoms is conflicting. There are few reliable data on its effectiveness for other disorders and symptoms.

Adverse effects: Adverse effects are uncommon. The most likely are headache and GI distress. Dizziness, diaphoresis, and hypotension (if high doses are taken) may occur.

There is no evidence that black cohosh interferes with any drugs. Theoretically, black cohosh is contraindicated in patients with aspirinSome Trade Names
BUFFERIN
ECOTRIN
GENACOTE
Click for Drug Monograph
sensitivity, liver disease, hormone-sensitive cancers (eg, certain kinds of breast cancer), stroke, or high BP. The US Pharmacopeia (USP) has recommended that black cohosh products be labeled with a warning declaring that they may be hepatotoxic.

Last full review/revision May 2009 by Ara DerMarderosian, PhD

Content last modified February 2012

Buy the Book

Mobile Versions

Back to Top

Previous: Overview of Dietary Supplements

Next: Chamomile

Audio
Figures
Photographs
Sidebars
Tables
Videos

Copyright     © 2010-2013 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Whitehouse Station, N.J., U.S.A.    Privacy    Terms of Use