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Epididymitis and Epididymo-orchitis

By

Patrick J. Shenot

, MD, Thomas Jefferson University Hospital

Last full review/revision May 2021| Content last modified May 2021
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Epididymitis is inflammation of the epididymis (the coiled tube on top of the testis that provides the space and environment for sperm to mature), and epididymo-orchitis is inflammation of the epididymis and testes.

  • Men may have swelling and tenderness or pain.

  • Epididymitis and epididymo-orchitis are diagnosed by physical examination, urinalysis, and sometimes Doppler ultrasonography.

  • Treatment includes antibiotics taken by mouth, bed rest, pain relievers, and ice packs applied to the scrotum.

Sometimes there is no infection of any kind. In such cases, doctors believe the epididymis becomes inflamed by reverse flow of urine into the epididymis, perhaps because of straining (as when men lift something very heavy).

Symptoms

Symptoms of epididymitis and epididymo-orchitis include

  • Swelling and tenderness of the affected area

  • Fluid around the testes (hydrocele)

  • Fever (sometimes)

The pain may become constant and severe. If the cause is a sexually transmitted disease, a discharge may be present. Rarely, an abscess (collection of pus) that feels like a soft lump develops in the scrotum.

Diagnosis

  • A doctor's evaluation

  • Urinalysis

Treatment

  • Antibiotics

  • Bed rest

  • Measures to relieve pain

Epididymitis and epididymo-orchitis are usually treated with antibiotics taken by mouth, bed rest, pain relievers, and ice packs applied to the scrotum. Immobilizing the scrotum with a jockstrap decreases pain from repetitive, minor bumps.

Abscesses usually require surgical drainage.

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