Merck Manual

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Syphilis—Secondary: Causing a Rash on the Soles
Syphilis—Secondary (Soles)
Syphilis—Secondary: Causing a Rash on the Soles

During the secondary stage of syphilis, a widespread rash may appear. Unlike rashes caused by most other diseases, this rash commonly appears on the palms or soles.

Image courtesy of Susan Lindsley via the Public Health Image Library of the Centers for Disease Control and Prevention.

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Syphilis