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Fatigue, swelling, slight tenderness, and appendicitis-like pain
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Painful urination and blood in urine
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Bones (mainly in children)
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Swelling and minimal pain
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Tissues covering the brain and spinal cord (meninges)
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Fever, headache, nausea, drowsiness, confusion, a stiff neck, and, if untreated, coma
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Pericardium (the two-layered membrane around the heart)
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Fever, chest pain, enlarged neck veins, shortness of breath
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Kidney damage with fever, back pain, and white blood cells (pus) and blood in the urine
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Swollen lymph nodes, which may become inflamed and tender and drain pus
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Reproductive organs in men
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Reproductive organs in women
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Chronic pelvic pain and sterility or a mislocated (ectopic) pregnancy
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Worsening or constant back pain, collapsed vertebrae, and leg paralysis
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