Merck Manual

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Injectable Antihyperglycemic Drugs*

Injectable Antihyperglycemic Drugs*

Drug

Some Side Effects

Glucagon-like peptide drugs

All glucagon-like peptide drugs can cause

  • Nausea

  • Vomiting

  • Diarrhea

They may also increase the risk of inflammation of the pancreas (pancreatitis) and some types of thyroid cancer

Albiglutide

Dulaglutide

Exenatide

Kidney damage (rare)

Extended-release exenatide

Injection site nodule

Liraglutide

Lixisenatide

Semaglutide

May worsen eye damage from diabetes (diabetic retinopathy)

Amylin-like drug

Pramlintide

Nausea

Low blood glucose levels

* Insulin is the most commonly used injectable antihyperglycemic drug.