Merck Manual

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Oxazolidinones

Oxazolidinones

Drug

Common Uses

Some Side Effects

Linezolid

Serious infections caused by susceptible gram-positive bacteria such as Staphylococcus (including methicillin-resistant Staphylococcus aureus [MRSA]), Streptococcus, and enterococci (including vancomycin-resistant enterococci) that are resistant to many other antibiotics

Nausea and diarrhea

Headache

Anemia and low white blood cell and platelet counts

Numbness and tingling in the hands and feet (peripheral neuropathy)

Visual disturbances

Serotonin syndrome (confusion, agitation, tremors, or coma) in some people who also take selective serotonin-reuptake inhibitors, monamine oxidase inhibitors, and some other drugs that affect serotonin levels.

Build up of lactic acid in the blood (lactic acidosis)

Tedizolid

Complicated skin infections due to susceptible bacteria, including MRSA

Gastrointestinal upset

Headache

Anemia and a low white blood cell count