Maternal Age and Risk of Having a Baby With a Chromosomal Abnormality*

Age of Woman

Risk of Any Chromosomal Abnormality

20

0.2%

30

0.3%

35

0.6%

40

1.6%

45

5.4%

49

15%

* This table includes only chromosomal abnormalities that can be detected by standard chromosomal testing. Risks of having a baby with submicroscopic chromosomal abnormalities (which can be detected only by special testing) are not included.

Hook EB. Rates of chromosome abnormalities at different maternal ages. Obstet Gynecol. 1981 Sep;58(3):282–285.