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Should be avoided in people with inflammatory bowel disease
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Temporary skin yellowing when used with another product that contains benzoyl peroxide
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Very rarely causes methemoglobinemia (a disorder that impairs the ability of the blood to carry oxygen)
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Frequent development of bacterial resistance
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Irritation, dry skin, redness
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Foam propellant is flammable. Fire, flame, and smoking should be avoided immediately after application.
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Possible bleaching of clothing and hair
Allergic reactions (rarely)
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Especially effective when combined with erythromycin or clindamycin
Benzoyl peroxide combined with erythromycin: Refrigeration sometimes required
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Unclogs pores (applied to the skin)
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Irritated skin (with dryness, redness, and scaling)
Sensitization of skin to sunlight
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Apparent worsening of acne when tretinoin is started, sometimes requiring 3 to 4 weeks before any improvement occurs
Requires use of protective clothing and sunscreen during sun exposure
Should be avoided during pregnancy
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Sensitization of skin to sunlight
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Apparent worsening of acne when tazarotene is started, sometimes requiring 3 to 4 weeks before any improvement occurs
Requires use of protective clothing and sunscreen during sun exposure
Should be avoided during pregnancy
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Increased sun sensitivity
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As effective as tretinoin but less irritating
Requires use of protective clothing and sunscreen during sun exposure
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May be used by itself or with tretinoin
Should be used cautiously in people with darker skin because of skin-lightening effects but can help lighten areas that leave dark skin after healing
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Over-the-counter product in form of a cream, lotion, or solution used in addition to prescription products but no longer commonly used
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Over-the-counter product in form of a wash, peel, mask, or lotion used in addition to prescription products
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Dryness, redness, and scaling of the skin
Increased sun sensitivity
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Requires use of protective clothing and sunscreen during sun exposure
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Kills bacteria (taken by mouth)
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Sensitization of skin to sunlight
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Inexpensive and safe, but must be taken on an empty stomach
Requires use of protective clothing and sunscreen during sun exposure
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Sensitization of skin to sunlight
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Requires use of protective clothing and sunscreen during sun exposure
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Most effective antibiotic according to some experts but is expensive
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Frequently, development of bacterial resistance to erythromycin
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Fewer side effects than erythromycin
Frequently, development of bacterial resistance to azithromycin
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Sensitization of skin to sunlight
Light-headedness,dizziness, or vertigo
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Requires use of protective clothing and sunscreen during sun exposure
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Trimethoprim/sulfamethoxazole
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Development of bacterial resistance to trimethoprim/sulfamethoxazole
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Unclogs pores (taken by mouth)
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Possible harm to a developing fetus
Possible effect on blood cells, the liver, and fat (triglyceride and cholesterol) levels
Dry eyes, chapped lips, and drying of the mucous membranes
Pain or stiffness of large joints and lower back with high dosages
Associated with depression, suicidal thoughts, attempted suicide, and (rarely) completed suicide, but whether isotretinoin is the actual cause is unknown
Unclear whether associated with new or worsened inflammatory bowel disease (Crohn disease and ulcerative colitis)
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For sexually active women, requires a pregnancy test before they start isotretinoin and at monthly intervals while they are taking the drug, plus use of two forms of contraception or sexual abstinence, beginning 1 month before they start the drug and continuing while they take it and for 1 month after they stop taking it
Requires blood tests to check whether the drug is affecting blood cells, the liver, or fat levels
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Blocks action of hormones (taken by mouth)
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High blood pressure (hypertension), blood clots, breakthrough vaginal bleeding (for example, between menstrual periods)
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For treatment of acne in females
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For treatment of acne in females
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