Merck Manual

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Some Causes of Noninfectious Meningitis

Some Causes of Noninfectious Meningitis

Type

Examples

Disorders

Cancer that has spread to the brain from other parts of the body (as can occur in leukemia, lymphoma, melanoma, or breast or lung cancer)

Rupture of a brain cyst

Drugs that suppress the immune system (used to treat autoimmune disorders and inflammation or to prevent rejection of a transplanted organ)

Azathioprine

Cyclosporine

Cytosine arabinoside

Immune globulin given by vein (intravenously)

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, naproxen, sulindac, and tolmetin

Other drugs

Certain antibiotics, such as ciprofloxacin, isoniazid, and penicillin

Carbamazepine (an anticonvulsant)

Phenazopyridine (used to treat urinary symptoms)

Ranitidine (used to treat stomach ulcers)

Sulfa drugs, such as trimethoprim-sulfamethoxazole (an antibiotic) and sulfasalazine (used to treat ulcerative colitis)

Substances that are injected into the subarachnoid space* for treatment or diagnosis

Anesthetics

Antibiotics

Chemotherapy drugs

Radiopaque contrast agents used in imaging tests

*The subarachnoid space contains cerebrospinal fluid and is located between middle and inner layers of tissue that cover the brain and spinal cord (meninges).