Merck Manual

Please confirm that you are not located inside the Russian Federation

honeypot link
Quick Facts

Pyoderma Gangrenosum

By

The Manual's Editorial Staff

Last full review/revision Jan 2021| Content last modified Jan 2021
CLICK HERE FOR THE PROFESSONAL VERSION
Get the full details
Topic Resources

What is pyoderma gangrenosum?

"Pyoderma" means a skin inflammation (swelling). "Gangrenosum" means skin ulcers with the death of tissue.

Pyoderma gangrenosum is a skin disease in which you get large sores on your skin, usually on your legs.

What causes pyoderma gangrenosum?

What are the symptoms of pyoderma gangrenosum?

Symptoms of pyoderma gangrenosum include:

  • A red bump or blister that becomes an open, painful sore that grows quickly

  • Raised area around the sore that is dark or purple

  • Fever

  • General feeling of illness

Sores from pyoderma gangrenosum can get worse from:

  • Biopsy (taking out part of the tissue to look at under a microscope)

  • Cleaning dead skin from the wound (called debridement)—although debridement usually helps wounds heal, debriding the sores of pyoderma gangrenosum makes them worse instead of better

Symptoms can sometimes spread to other areas, such as your belly area, bones, lungs, or muscles.

How can doctors tell if I have pyoderma gangrenosum?

Doctors can usually tell if you have pyoderma gangrenosum by looking at the sores.

How do doctors treat pyoderma gangrenosum?

Doctors treat pyoderma gangrenosum using:

  • Dressings to protect your skin

  • Corticosteroids

  • Sometimes medicine to calm down your immune system

Doctors don't usually do surgery because it makes the sores worse.

NOTE: This is the Consumer Version. DOCTORS: CLICK HERE FOR THE PROFESSONAL VERSION
CLICK HERE FOR THE PROFESSONAL VERSION
Others also read
Test your knowledge
Separation Anxiety and Stranger Anxiety
An important part of normal development is an infant’s growing attachment to its parents. As this bond strengthens, the infant may express fear or anxiety when the parents leave. This “separation anxiety” typically begins at around 8 months of age and resolves at around 24 months of age. Which of the following is the normal and expected infant behavior in reaction to a parent leaving the room during the time period of separation anxiety?
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID

Also of Interest

Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
TOP