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Korsakoff Psychosis

(Korsakoff's Amnestic Syndrome; Korsakoff's Psychosis; Korsakoff Syndrome; Korsakoff's Syndrome)

By

Gerald F. O’Malley

, DO, Grand Strand Regional Medical Center;


Rika O’Malley

, MD, Grand Strand Medical Center

Last full review/revision Jun 2020| Content last modified Jun 2020
CLICK HERE FOR THE PROFESSONAL VERSION

Symptoms of Korsakoff Psychosis

People with Korsakoff psychosis lose their memory for recent events. Memory of remote events is less affected. Memory can be so poor that people often make up stories, sometimes very convincingly, to try to cover up the inability to remember (called confabulation). They lose all sense of time. People become confused and apathetic and may not respond to events, even frightening ones. People also have all the symptoms of Wernicke encephalopathy, including profound ataxia (wide-based stumbling gait) and difficulty controlling eye movements.

Diagnosis of Korsakoff Psychosis

  • History of a condition known to cause Korsakoff psychosis, such as severe chronic alcohol use disorder

Doctors base a Korsakoff psychosis diagnosis on symptoms, particularly confabulation, in people with conditions that can cause Korsakoff psychosis, such as severe chronic alcohol use disorder Alcohol Alcohol (ethanol) is a depressant. Consuming large amounts rapidly or regularly can cause health problems, including organ damage, coma, and death. Genetics and personal characteristics may... read more . Doctors need to rule out other causes of the symptoms, such as infection.

Treatment of Korsakoff Psychosis

  • Thiamin

  • Fluids

Treatment for Korsakoff psychosis consists of the vitamin thiamin and hydration. Unfortunately, despite treatment, reversal of symptoms is poor and recovery is unlikely.

More Information about Korsakoff Psychosis

Drugs Mentioned In This Article

Generic Name Select Brand Names
KETALAR
DELATESTRYL
ADDERALL XR 10
ATIVAN
COMMIT, NICORETTE, NICOTROL
No US brand name
No US brand name
OXYCONTIN
TYLENOL
QUALAQUIN
MARINOL
DEMEROL
DURAMORPH PF, MS CONTIN
TALWIN
DILAUDID
DOLOPHINE
ACTIQ, DURAGESIC, SUBLIMAZE
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