Persistent genital arousal disorder is excessive unwanted physical (genital) arousal, involving increased blood flow to the genital organs and, in women, increased vaginal secretions, without any desire for sexual activity.
The cause of persistent genital arousal disorder is unknown. It is rare and has mainly occurred in women.
In most cases, persistent genital arousal disorder does not have a clear cause. However, several factors may contribute to it. These may include problems with blood vessels, nerve-related conditions (such as issues affecting spinal nerves), or medication-related effects (such as starting or suddenly stopping certain antidepressants). This disorder may also occur along with other conditions, such as overactive bladder (a frequent or urgent need to urinate) or restless legs syndrome (an uncomfortable urge to move the legs).
Doctors diagnose persistent genital arousal disorder when a woman has characteristic symptoms that are causing distress.
Treatment of Persistent Genital Arousal Disorder
Treatment of cause, if identified
Medications
Psychological therapies
Treatment of persistent genital arousal disorder is unclear and depends on whether the cause can be identified. Simple recognition of the existence of this disorder, with reassurance that it can spontaneously resolve, may be helpful. Treatment options range from medical to behavioral interventions and, rarely, surgical procedures. Because PGAD can have several possible contributing factors, treatment is often individualized, and more than 1 approach may be needed.
The main goal of treatment is to reduce or manage factors that may be contributing to symptoms. Medications that may be used to help manage symptoms include pain relievers, medications that help calm nerve activity, and botulinum toxin (Botox) injections.



