Merck Manual

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Introduction to Hypersensitivity and Inflammatory Skin Disorders


Julia Benedetti

, MD, Harvard Medical School

Last full review/revision Jul 2020| Content last modified Jul 2020
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The immune system plays a significant role in a large number of skin disorders, including dermatitis, sunlight reactions, and bullous diseases. Although all of these disorders involve some level of inflammation, certain skin disorders are primarily characterized by their inflammatory component or as a hypersensitivity reaction, be it to a drug, infection, or cancer. These disorders include

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