Many drugs cause nausea, vomiting, and diarrhea as adverse effects. A detailed drug history must be obtained. In mild cases, cessation followed by reuse of the drug may establish a causal relationship. Commonly responsible drugs include antacids containing magnesium, antibiotics, antihelminthics, cytotoxics (used in cancer therapy), colchicine, digoxin, heavy metals, laxatives, and radiation therapy. Use of antibiotics may lead to Clostridium difficile–induced diarrhea Clostridioides (formerly Clostridium) difficile–Induced Diarrhea Toxins produced by Clostridioides difficile strains in the gastrointestinal tract cause pseudomembranous colitis, typically after antibiotic use. Symptoms are diarrhea, sometimes bloody, rarely... read more .
Iatrogenic, accidental, or intentional heavy-metal poisoning frequently causes nausea, vomiting, abdominal pain, and diarrhea.
Laxative abuse, sometimes denied by patients, may lead to weakness, vomiting, diarrhea, electrolyte depletion, and metabolic disturbances.
Various plants Plant Poisoning A few commonly grown plants are highly poisonous, and many plants are moderately poisonous (see table Moderately Poisonous Plants). Few plant poisonings have specific antidotes. Most plant ingestions... read more and mushrooms Mushroom Poisoning Numerous mushroom species cause toxicity when ingested. Symptoms vary by species. Identification of specific species is difficult, so treatment usually is guided by symptoms. (See also General... read more cause a syndrome of gastroenteritis.
(See also Gastroenteritis Gastroenteritis Gastroenteritis is inflammation of the lining of the stomach and small and large intestines. Most cases are infectious, although gastroenteritis may occur after ingestion of drugs and chemical... read more .)
Drugs Mentioned In This Article
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