(See also Overview of Vascular Bleeding Disorders Overview of Vascular Bleeding Disorders Bleeding may result from abnormalities in Platelets Coagulation factors Blood vessels Vascular bleeding disorders result from defects in blood vessels, typically causing cutaneous or mucosal... read more .)
Purpura refers to purplish cutaneous or mucosal lesions caused by hemorrhage. Small lesions (< 2 mm) are termed petechiae, and large lesions are termed ecchymoses or bruises.
Senile purpura typically affects older patients as their dermal tissues atrophy and blood vessels become more fragile. Patients develop persistent dark purple ecchymoses, which are characteristically confined to the extensor surfaces of the hands and forearms. New lesions appear without recognized trauma and then resolve over several days, leaving a brownish discoloration caused by deposits of hemosiderin. This discoloration may clear over weeks to months or may be permanent. The skin and subcutaneous tissue of the involved area often appear thinned and atrophic.
Medications (eg, corticosteroids, warfarin, aspirin, clopidogrel) may exacerbate the ecchymoses.
No treatment hastens lesion resolution or is needed. Although cosmetically displeasing, the disorder has no health consequences and does not herald severe bleeding elsewhere.
Drugs Mentioned In This Article
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