Merck Manual

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Oligella Infections

By

Larry M. Bush

, MD, FACP, Charles E. Schmidt College of Medicine, Florida Atlantic University;


Maria T. Vazquez-Pertejo

, MD, FACP, Wellington Regional Medical Center

Reviewed/Revised Sep 2022
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Oligella species are gram-negative organisms that cause infection primarily of the genitourinary tract.

The genus Oligella contains 2 species, Oligella urethralis and Oligella ureolytica.

O. ureolytica also occurs primarily in the urine, usually from patients with long-term urinary catheters or other urinary drainage systems. These patients have a propensity to develop urinary stones, possibly because the organism hydrolyzes urea and alkalinizes the urine, leading to precipitation of phosphates. Bacteremia has occurred in a patient with obstructive uropathy.

Diagnosis of Oligella infections is by culture.

Because these organisms are rarely isolated, antimicrobial susceptibility data are limited; most are sensitive to beta-lactam antibiotics. However, a beta-lactamase–producing strain and strains resistant to ciprofloxacin have been identified.

Drugs Mentioned In This Article

Drug Name Select Trade
Aluvea , BP-50% Urea , BP-K50, Carmol, CEM-Urea, Cerovel, DermacinRx Urea, Epimide-50, Gord Urea, Gordons Urea, Hydro 35 , Hydro 40, Kerafoam, Kerafoam 42, Keralac, Keralac Nailstik, Keratol, Keratol Plus, Kerol, Kerol AD, Kerol ZX, Latrix, Mectalyte, Nutraplus, RE Urea 40, RE Urea 50 , Rea Lo, Remeven, RE-U40, RYNODERM , U40, U-Kera, Ultra Mide 25, Ultralytic-2, Umecta, Umecta Nail Film, URALISS, Uramaxin , Uramaxin GT, Urea, Ureacin-10, Ureacin-20, Urealac , Ureaphil, Uredeb, URE-K , Uremez-40, Ure-Na, Uresol, Utopic, Vanamide, Xurea, X-VIATE
Cetraxal , Ciloxan, Cipro, Cipro XR, OTIPRIO, Proquin XR
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NOTE: This is the Professional Version. CONSUMERS: View Consumer Version
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