Merck Manual

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Oligella Infections

By

Larry M. Bush

, MD, FACP, Charles E. Schmidt College of Medicine, Florida Atlantic University;


Maria T. Vazquez-Pertejo

, MD, FACP, Wellington Regional Medical Center

Last full review/revision Jul 2020| Content last modified Mar 2021
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Oligella species are gram-negative organisms that cause infection primarily of the genitourinary tract.

The genus Oligella contains 2 species, Oligella urethralis and Oligella ureolytica.

O. ureolytica also occurs primarily in the urine, usually from patients with long-term urinary catheters or other urinary drainage systems. These patients have a propensity to develop urinary stones, possibly because the organism hydrolyzes urea and alkalinizes the urine, leading to precipitation of phosphates. Bacteremia has occurred in a patient with obstructive uropathy.

Diagnosis of Oligella infections is by culture.

Because these organisms are rarely isolated, antimicrobial susceptibility data are limited; most are sensitive to beta-lactam antibiotics. However, a beta-lactamase–producing strain and strains resistant to ciprofloxacin have been identified.

Drugs Mentioned In This Article

Drug Name Select Trade
CILOXAN, CIPRO
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