Merck Manual

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Biotin and Pantothenic Acid

By

Larry E. Johnson

, MD, PhD, University of Arkansas for Medical Sciences

Last full review/revision Nov 2020| Content last modified Nov 2020
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Biotin acts as a coenzyme for carboxylation reactions essential to fat and carbohydrate metabolism. Adequate intake for adults is 30 mcg/day.

Pantothenic acid is widely distributed in foods; it is an essential component of coenzyme A. Adults probably require about 5 mg/day. A beneficial role for pantothenic acid supplementation in lipid metabolism, rheumatoid arthritis (RA), or athletic performance remains unproved.

Isolated deficiency of biotin or pantothenic acid virtually never occurs.

(See also Overview of Vitamins.)

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