Merck Manual

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Overview of Hereditary Periodic Fever Syndromes

By

Apostolos Kontzias

, MD, Stony Brook University School of Medicine

Last review/revision Jan 2022 | Modified Sep 2022
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Hereditary periodic fever syndromes are hereditary disorders characterized by recurrent fever and other symptoms that are not explained by other causes.

Most patients develop symptoms during childhood; < 10% develop symptoms after age 18. Disorders best characterized are

Other disorders include

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NOTE: This is the Professional Version. CONSUMERS: View Consumer Version
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