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antibiotic that has a unique mechanism of action. It binds to the bacterial cell membranes, causing rapid depolarization of the membrane due to potassium efflux and associated disruption of DNA, RNA, and protein synthesis; the result is rapid concentration-dependent bacterial death.
Gram-positive bacteria (broad-spectrum activity)
Multidrug-resistant gram-positive bacteria
However, methicillin-resistant S. aureus
Use During Pregnancy and Breastfeeding
Myopathy
Dosing is adjusted for renal failure.
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