Usually, the main symptoms of normal-pressure hydrocephalus are general unsteadiness and loss of balance, and the feet may seem to stick to the floor.
Dementia may not develop until late in the disorder.
Doctors usually do magnetic resonance imaging to check for excess fluid around the brain and do a spinal tap or place a temporary drain into the spinal cord to remove any excess fluid.
Placing a piece of plastic tubing (a shunt) in the brain to drain the excess fluid may significantly lessen some symptoms, but it may benefit mental function less.
(See also Overview of Delirium and Dementia Overview of Delirium and Dementia Delirium and dementia are the most common causes of mental (cognitive) dysfunction—the inability to acquire, retain, and use knowledge normally. Although delirium and dementia may occur together... read more and Dementia Dementia Dementia is a slow, progressive decline in mental function including memory, thinking, judgment, and the ability to learn. Typically, symptoms include memory loss, problems using language and... read more .)
Normally, the fluid that surrounds the brain and protects it from injury (cerebrospinal fluid) is continuously produced in the spaces within the brain (ventricles), circulates in and around the brain, and is reabsorbed. Normal-pressure hydrocephalus is thought to occur when this fluid is not reabsorbed normally, causing it to accumulate. The amount of fluid in the ventricles increases and the brain is then pushed outward.
Normal-pressure hydrocephalus is classified as one of the following:
Secondary: When it is caused by another disorder (such as a subarachnoid hemorrhage Subarachnoid Hemorrhage (SAH) A subarachnoid hemorrhage is bleeding into the space (subarachnoid space) between the inner layer (pia mater) and middle layer (arachnoid mater) of the tissues covering the brain (meninges)... read more , meningitis Acute Bacterial Meningitis Acute bacterial meningitis is rapidly developing inflammation of the layers of tissue that cover the brain and spinal cord (meninges) and of the fluid-filled space between the meninges (subarachnoid... read more , or a head injury Overview of Head Injuries Head injuries that involve the brain are particularly concerning. Common causes of head injuries include falls, motor vehicle crashes, assaults, and mishaps during sports and recreational activities... read more )
Idiopathic: When no cause can be identified
Symptoms of Normal–Pressure Hydrocephalus
Usually, the main symptoms of normal-pressure hydrocephalus are general unsteadiness and loss of balance. People typically have an abnormally slow, unsteady, wide-legged walk. The feet may seem to stick to the floor (called a magnetic gait). People also have urinary incontinence and a tendency to fall.
Dementia Dementia Dementia is a slow, progressive decline in mental function including memory, thinking, judgment, and the ability to learn. Typically, symptoms include memory loss, problems using language and... read more may not develop until late in the disorder. Often, the first signs of dementia are difficulty planning, organizing, putting ideas or doing actions for a task in the right order (sequencing), thinking abstractly, and paying attention. Memory tends to be lost later.
Diagnosis of Normal–Pressure Hydrocephalus
A doctor's evaluation
Brain imaging, usually magnetic resonance imaging
Lessening of symptoms after removal of cerebrospinal fluid
Doctors may suspect normal-pressure hydrocephalus when people have the three typical symptoms:
However, the diagnosis of normal-pressure hydrocephalus cannot be based on symptoms alone, particularly in older people. Other dementias can cause similar symptoms, and in older people, many conditions can make walking difficult or cause urinary incontinence.
Diagnosis of dementia
Doctors base a diagnosis of dementia on the following:
Symptoms, which are identified by asking the person and family members or other caregivers questions
Results of a physical examination, including a neurologic examination Neurologic Examination When a neurologic disorder is suspected, doctors usually evaluate all of the body systems during the physical examination, but they focus on the nervous system. Examination of the nervous system—the... read more
Results of a mental status test
Results of additional tests, such as computed tomography (CT) or magnetic resonance imaging (MRI)
Mental status testing Mental Status When a neurologic disorder is suspected, doctors usually evaluate all of the body systems during the physical examination, but they focus on the nervous system. Examination of the nervous system—the... read more , consisting of simple questions and tasks, helps doctors determine whether people have dementia.
Neuropsychologic testing, which is more detailed is sometimes needed. This testing covers all the main areas of mental function, including mood, and usually takes 1 to 3 hours. This testing helps doctors distinguish dementia from other conditions that can cause similar symptoms, such as age-associated memory impairment Dementia , mild cognitive impairment Dementia , and depression Dementia .
Information from the above sources can usually help doctors rule out delirium as the cause of symptoms (see table Comparing Delirium and Dementia Comparing Delirium and Dementia ). Doing so is essential because delirium, unlike dementia, can often be reversed if promptly treated. Differences between the two include the following:
Dementia affects mainly memory, and delirium affects mainly attention.
Dementia typically begins gradually and has no definite beginning point. Delirium begins suddenly and often has a definite beginning point.
Diagnosis of normal-pressure hydrocephalus
Brain imaging, usually magnetic resonance imaging (MRI) is done to check for excess cerebrospinal fluid. Finding excess fluid and other characteristic changes in the brain supports the diagnosis of normal-pressure hydrocephalus but does not confirm it.
To help with the diagnosis, doctors do a spinal tap Spinal Tap Diagnostic procedures may be needed to confirm a diagnosis suggested by the medical history and neurologic examination. Electroencephalography (EEG) is a simple, painless procedure in which... read more (lumbar puncture) or place a temporary drain into the spinal cord to remove excess cerebrospinal fluid. If these procedures relieve symptoms, usually by improving gait, normal-pressure hydrocephalus is more likely, and treatment is more likely to be effective.
Treatment of Normal–Pressure Hydrocephalus
A shunt in the ventricles of the brain
Treatment of normal-pressure hydrocephalus consists of placing a piece of plastic tubing (a shunt) in the ventricles of the brain and running it under the skin, usually to the abdomen (ventriculoperitoneal shunting). Cerebrospinal fluid is then drained away from the brain. The effects of this treatment may not be evident for several hours. This procedure may significantly improve the ability to walk and function and may lessen incontinence. However, mental function improves less and in fewer people. Thus, early diagnosis is important, so that people can be treated before dementia develops.
Safety and supportive measures
Generally, the environment should be bright, cheerful, safe, stable, and designed to help with orientation. Some stimulation, such as a radio or television, is helpful, but excessive stimulation should be avoided.
Structure and routine help people with dementia stay oriented and give them a sense of security and stability. Any change in surroundings, routines, or caregivers should be explained to people clearly and simply.
Following a daily routine for tasks such as bathing, eating, and sleeping helps people with dementia remember. Following a regular routine at bedtime may help them sleep better.
Activities scheduled on a regular basis can help people feel independent and needed by focusing their attention on pleasurable or useful tasks. Such activities should include physical and mental activities. Activities should be broken down in small parts or simplified as the dementia worsens.
Care for caregivers
Caring for people with dementia is stressful and demanding, and caregivers may become depressed and exhausted, often neglecting their own mental and physical health. The following measures can help caregivers (see table Caring for Caregivers Caring for Caregivers ):
Learning about how to effectively meet the needs of people with dementia and what to expect from them: Caregivers can get this information from nurses, social workers, organizations, and published and online materials.
Seeking help when it is needed: Caregivers can talk to social workers (including those in the local community hospital) about appropriate sources of help, such as day-care programs, visits by home nurses, part-time or full-time housekeeping assistance, and live-in assistance. Counseling and support groups can also help.
Caring for self: Caregivers need to remember to take care of themselves. They should not given up their friends, hobbies, and activities.
The following are some English-language resources that may be useful. Please note that THE MANUAL is not responsible for the content of these resources.
Dementia.org: This web site provides information about the causes, symptoms, treatments, and stages of dementia.
Health Direct: Dementia Video Series: These videos provide general information about dementia, recommendations about the warning signs of dementia, treatment and research, and caring for a person with dementia. It also provides links to articles on similar topics.
National Institute of Neurological Disorders and Stroke's Dementia Information Page: This web site provides information about treatments and prognosis, and links to clinical trials.