Aneurysms may occur in any artery. (See also Aortic Branch Aneurysms and Aneurysms of Arteries in the Arms, Legs, and Heart.)
Many cerebral aneurysms result from a weakness in the artery wall that is present at birth (congenital). Others are caused by atherosclerosis (buildup of plaque or fatty material in the wall of blood vessels). People may have only one cerebral aneurysm or several. Others result from bacterial or fungal infections in the wall of the artery that develop after recreational use of intravenous drugs such as heroin. Such infections usually start elsewhere in the body, typically in a heart valve, before spreading to the wall of the artery.
Most cerebral aneurysms do not cause symptoms unless they are large or rupture.
Larger unruptured cerebral aneurysms can push on brain tissue and nerves and cause headache, which may feel pounding in time with the pulse (pulsatile). Less often, people may have dilated pupils and/or symptoms of a stroke, such as weakness or paralysis on one side of the body.
Rupture of a cerebral aneurysm causes immediate, severe headache that is sometimes described as coming on like a thunderclap. If the ruptured aneurysm bleeds into the brain tissue (intracerebral hemorrhage), people often develop a symptoms of a stroke (which is typically caused by blood clots rather than bleeding). The bleeding can increase the pressure in the brain, which can lead to coma and sometimes death.
Because cerebral aneurysms are near the brain and are usually small, their diagnosis and treatment differ from those of other aneurysms.
The diagnosis of a cerebral aneurysm is made by specialized computed tomography (CT) or magnetic resonance imaging (MRI) scans. These specialized scans are called CT angiography or magnetic resonance angiography.
Infected aneurysms of the cerebral arteries are particularly dangerous, making early treatment important. Diagnosis of an infected aneurysm is made by CT angiography, blood tests that indicate increased levels of inflammation (such as an elevated C-reactive protein level or an elevated erythrocyte sedimentation rate), and blood cultures (samples of blood that are grown in a laboratory) that show the growth of microorganisms (such as bacteria or fungi).
Treatment of cerebral aneurysms often involves surgical repair of the aneurysm. Surgical repair involves placing a clip to close off the aneurysm. The clip is placed where the aneurysm pouches out from the main artery.
Sometimes a less invasive treatment (endovascular coiling) can be done. Endovascular coiling involves inserting a small but long flexible plastic tube (catheter) into an artery in the thigh. The catheter is then pushed through the arteries of the body to the aneurysm in the brain artery. Small metal coils are injected through the catheter into the opening of the aneurysm to block blood flow into it, thereby allowing the aneurysm to shrink.
When the aneurysm is infected, antibiotics or antifungal drugs are given.